Sodium Copper Chlorophyllin: A Potential Enterovirus Treatment
Enterovirus A71 (EV-A71), one of more than 100 non-polio enteroviruses, was first identified in the U.S. in 1969 and is a common cause of hand, foot, and mouth disease in infants and young children across the globe. According to CDC.gov, for most people, symptoms are mild, and the virus will clear on its own. In rare cases, the virus has caused severe neurological diseases, such as meningitis, encephalitis, and acute flaccid myelitis. There are currently no specific treatments or antiviral medications available for people who become infected with EV-A71.
This study tested the effectiveness of sodium copper chlorophyllin (CHL) against EV-A71. Results from the study showed that CHL demonstrated “potent inhibitory activity” against infection, at a “low micromolar concentration with excellent safety.” Sodium copper chlorophyllin also “blocked the entry of EV-A71 into the host cell at the post-attachment stage.”
An abstract of the full study can be found here: https://pubs.acs.org/doi/abs/10.1021/acsinfecdis.0c00096.